The film revolves around Prem (Salman Khan), a young man from a wealthy family who falls in love with Kunj (Madhuri Dixit), the sister of his best friend, Rajesh Nath (Mukul Dutt). As their romance blossoms, Prem and Kunj must navigate their relationships with their families, particularly Prem's mother, Pooja (Sushila Raaj), and Kunj's family, the eccentric and endearing Nath family.

The film's soundtrack, composed by Viju Shah and written by R. D. Burman, became a huge success, with iconic songs like "Didi Tera Devar Deewana," "Hum Aapke Hain Koun," and "Tujhe Dekha To." The songs were beautifully choreographed by Saroj Khan, with memorable dance sequences featuring Madhuri Dixit and Salman Khan.

"Hum Aapke Hain Koun..!" achieved massive commercial success, grossing over ₹38 crores at the box office. The film received positive reviews from critics, with praise for its storytelling, performances, and music. The film's success marked a turning point in Salman Khan's career, cementing his status as a leading hero in Bollywood. The film also revitalized Madhuri Dixit's career, solidifying her position as one of the most popular actresses of the 1990s.